ABSTRACT
Background:Arterialhypoxaemiaisthecommonestcomplication,sincerespiratory depressantdrugsareusedforpremedication,andtheairwayisalsopartially occludedbythebronchoscope.Thestudyisthereforedesignedtofindoutthechangesinarterialoxygen tensionduring (FOB)alongwitheffectoncentral hemodynamics, pre andpost procedure ECGand PFT.Objectives were tofind out thechanges in arterial oxygentension during FOB, to study the effects of FOBon central hemodynamics, electrocardiographicallyand pulmonaryfunction tests.Methods:One hundred patients aged above 20 years undergoing FOB were evaluated for the arterial oxygen tension and cardiac rhythm changes at KNCH, Jodhpur during 12 months study period from 2019 to 2020.Results:All patients developed a fall in PaO2following FOB but hypoxaemia was noted only in 18 cases. Bronchial washing, punch biopsy and brush biopsy did contribute to hypoxaemia significantly. There was a uniform rise in heart rate in all the patients after FOB which was statistically significant. There was slight sinus tachycardia inmostofthecases although ECG indicated no major arrhythmias.ThepulmonaryfunctionswhichincludechangeinVC,FVC, FEV1andPEFR after FOB, on statisticallycomparisonnostatistical difference could be observed. Therewasnosignificantchangein PaCO2level and pH level.MeanofSBP andmeanofDBPwasstatistically significant.Conclusions:All patients showed a decline in arterial PaO2after FOB which was highly significant. There was slight sinus tachycardia in most of cases. FOB itself does not endanger the patients with any significant or serious complications.
ABSTRACT
Background: Respiratory diseases commonly present and are mostly diagnosed by routine clinical assessment and noninvasive investigations. Bronchoscopy a novel diagnostic tool used in diagnosis of various infectious, inflammatory and neoplastic pulmonary diseases by retrieving samples from bronchial, alveolar and interstitial compartments of patients with lung infiltrates. We prospectively assessed diagnostic utility of bronchoscopy in patients who had respiratory symptoms, radiographic infiltrates and sputum smear is negative for acid-fast bacilli (AFB). Despite, recent technical innovations in bronchoscopy, routine FOB is practiced with high yield and cost effectiveness.Methods: A prospective study was performed in which bronchoscopy was performed in 40 patients between August 2018 and January 2019, who had respiratory symptoms, radiographic findings not consistent with any specific diagnostic entity and had sputum smear negative for AFB.Results: Out of total 40 patients, most 30 (75%) patients were from rural areas, more than half 24 (60%) of the patients were males. Out of total 21 (52%) of patients were current smokers. Most common presenting symptoms were cough 22 (55%) and hemoptysis 8 (20%) followed by fever 6 (15%) and weight loss 4 (10%). Tuberculosis was confirmed in 18 (45%) patients. Non tubercular diseases were diagnosed in 22 (55%). Interstitial lung disease (ILD) was diagnosed in 5 (12.5%), lung cancer in 5%, bronhiectasis in 7.5%, pneumonia in 12.5%, lung abscess in 2.5% and non-specific infection in 15%.Conclusions: Diagnostic utility of flexible bronchoscopy is ever growing and has certainly taken a turn from being a luxury to near necessity today. Its association with trivial complications makes it a safe procedure. Hence bronchoscopy should be considered in the evaluation of patients with respiratory symptoms, indefinate radiographic infiltrates and negative sputum AFB test.